GLP-1 Weight Loss Cost Calculator

GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have become some of the most widely discussed weight loss treatments available. These medications work by mimicking the GLP-1 hormone that regulates appetite and blood sugar, leading to reduced food intake and significant weight loss. Clinical trials have shown average weight loss of 15 to 22 percent of body weight over 12 to 18 months, though individual results vary widely based on dosage, diet, exercise, and metabolic factors.

The cost of GLP-1 medications remains one of the biggest barriers to access. Without insurance, brand-name semaglutide injections like Wegovy can cost over $1,300 per month, while Mounjaro and Zepbound typically run around $1,000 per month at retail price. Ozempic, originally approved for type 2 diabetes, costs roughly $900 per month when used off-label for weight management. The emergence of compounded generic semaglutide has brought monthly costs down to approximately $200 to $400 for some patients, though availability and regulatory status can change.

Insurance coverage for GLP-1 weight loss medications varies dramatically by plan and by diagnosis. Many insurers cover Ozempic and Mounjaro for type 2 diabetes but deny coverage for weight loss alone, while Wegovy and Zepbound, specifically approved for chronic weight management, may require prior authorization or proof of a qualifying BMI. Manufacturer savings programs, pharmacy discount cards, and employer wellness benefits can significantly reduce out-of-pocket costs. Always check with your insurance provider and prescribing physician to understand your specific coverage before committing to a treatment plan.